I've landed on an 18" lightweight 6mm Creed with 108/109 ELDM (upgrade from 105 AMAX) for walking/stalking, and a 25 Creed with 131 Blackjack/133 Bergers for stand hunting.
@TxLite with a 300 yard limit, I wouldn't be too terribly worried. Any of these calibers will do what you want.
16" will certainly limit your velocity, but at 300 you'll sill have plenty for medium game.
Decide what your priority is. If it's recoil, go 22 creed or 6 ARC. If it's more speed or...
With an 8 twist you can shoot all the Berger 133/135 and the Hornady 134
These are great options with high BC and reportedly do very well on game.
I've killed a pile of deer with the discontinued 131 Blackjack Ace with a 25 creed at distances up to 600 yards with excellent results
One of my favorite builds. I bought the Savage new and installed a new Proof Research 6.5 Creedmoor 8 twist 24" carbon fiber barrel. Load development was a breeze with this barrel, I shot 143 gr ELDX blem bullets over H4350 into a 8.8" group at 1,000 yards. I hunted with it twice and got 3 deer...
I'm the original owner, was mounted on a 25 Creedmoor. Couple small dings from bumping other rifles in the safe, otherwise excellent condition. I've shot this scope at 1000 yards and hunted with it a couple times. Performs flawlessly.
Illuminated red reticle. Ships in factory box with NF...