Came from Maine to Colorado last year driving. While Maine doesn't have altitude, no peak higher then 6000, but we have many mountains and a lot that go from just above sea level, to 3000 plus feet. But where I live is only 300 feet above elevation. So the hiking and leg strength wasn't an issue. I did take some anti altitude sickness pills on the way out. We called first night at 8400 feet, and climbed to almost 10,000 by the end of the next day. Camped there that night. Had a slight headache the next morning. Never had an issue the rest of trip. Didn't go higher than 10000. Everyone is differnt, so not sure if that helps. I also did a lot of heavy pack training the last 4 months before trip. For what it's worth I feel like am quite physically fit.
I've hunted further north; 49, 45, 36, 231 also camped in 48.
