I’ve used the 140 Fusion out of a 280. I found that while it’s a bonded bullet, it performed more like a traditional cup and core. I had a couple fragment into 3-4 fairly large pieces on cow elk. Killed the elk but was not confidence inspiring as those large jagged fragments could have easily taken a different route and led to a rodeo.
The 150 7mm RM load is a little faster than the 140 280 load. So for me, I would be placing it broadside at close to moderate range. Further out it should do fine. I have seen several Alaskans speak highly of the 150 load out of a 270 Win. for Moose and Griz. I think the difference is the lower velocity.
I’d use the 175 out of a 7mm RM.