Within a couple hundred yards it's within the kill zone on a medium sized animal (a couple inches) but I re-zero if switching (and generally don't switch) up to 160 accubond... more because moving from Remington to Nosler than bullet size (140 corelokt vs 160 accubond). I also don't know if a different barrel would yield bigger variance. You can also find custom loaded 160 a-frames online if you don't like Nosler.clock: since you shoot 4 different weights hows the point of Impact? are you always changing the scope?
Oregonmuley that is a awesome looking rifle. I hear you on the 7-08! amazing cartridge!! I've contemplated going to another 7-08 over the 280. Not a lot difference in them. We have 2 7mm-08's in our house and they are a great gun, and I wouldn't be ashamed of having another. They have taken deer and elk in our house.