If you go with the 44 mag revolver, I would recommend the Diamond D holster, specifically the guides choice chest rig. My bucket list includes some Alaska hunting and fishing at some point in my life, so I bought a 454 Taurus for a price I couldn't pass up. Then I researched holsters, and found/bought that one. Its a high quality holster for sure. I have only carried my gun using that holster a few times, and yes it is quite heavy for a backcountry trip. Now having said all that, I am now on the hunt for a glock 10mm at a decent price. Once I have it, I plan on getting a holster (probably kydex) that would mount to my hip belt of my backpack set up. 10mm would be carried for now (lower 48 hunting where there are no griz), and the 454 for areas where there is a larger danger of an encounter with griz/Mr. Brown. Hopefully someday I will find myself salmon fishing (or hunting) in Alaska and have a need to carry my 454...LOL.
One negative to the chest holster is might not work now that I have an Alaskan Guide Creations bino harness, now that you mentioned it...LOL. I may have to dig both set ups out and see if they would work together. The chest rig holster can be moved off center to a point, but not sure if they could be worn simultaneously and still be functional. Glad this came up....because its something I will have to look into myself to see. Im BRAND new to the AGC bino harness. I have seen lots of guys with them and thought they would be very bulky (worse than the chest rig holster), but I have committed to trying one (the AGC bino harness) this year to see how I like running it.