Which gun to take

[wildtrader]

i like my 7mm, larger bullet less damage to carcass

 

[Dust Rider]

Antelope can be easy to sneak up close to depending on the terrain. Work the landscape and you can get within 200 yards. I have taken over 20 of them under 200 yards.
Last year I notched 3 speed goat tags and longest shot was 160 yards.

 

[eaglemountainman]

Unless you choose to do so, there should be very few occasions that require you to shoot past 300 yds.

As far as your choices, I'd call it a pick em. Use the one you're most comfortable with as your primary and bring another along as a back up in case of something unforeseen.

Antelope only yield about 35# of boned meat so I don't want to lose any to bullet trauma. I use Barnes TTSXs and shoot for heart/lungs.

 

[Seamaster]

If I had to pick among those rifles for pronghorns it would be the 243. Any bullet (other than a varmint bullet) will do well for a 100 lb. ppronghorn.