I try and give them a wide berth. I've met some nice guys wrangling the horses, or cooking, who usually say "Holy S%^*!! You hiked back in here??" Those guys can be pretty friendly. I've had issues with guides being disrespectful of our space though. We were set up on a canyon (which we have hunted for years, from the same camp), quite obviously glassing it and prepping to go down on opening morning (multiple spotters on tripods, tents carefully tucked back out of wind and sight over the ridge), and had guides ride right up the day before, ask if we were hunting the basin, to which we said yes, planning on getting into this herd we are glassing.
Come 4 am on the opener, they ride right through our camp as we are eating breakfast (without a word, as you could tell they had decided to get into the canyon before us, to beat us to the elk), drop into our basin, ride right into and blow out the herd we were glassing (which you could see quite plainly from where we were set up the day before), so they could get to the next ridge over, to find a $10k bull they spotted the day before from their plane. Guys did this a couple years back, pushed all the elk further back into the canyons (you can't ride horses in without getting spotted the way it's set up, you have to enter quietly in the timber on foot to not blow out the basin, they knew damn well they were ruining our opening morning hunt). Client shot a nice 6x6 (2 guides, 1 hunter) but you could tell he felt like a dick riding back by us as we humped another couple miles in to find new elk, instead of killing one of the herd we had glassed up for the opener.
Understandably, this was public land, and I'm sure they had been keeping tabs on that bull for the client, but it was still an asshole move. My buddy actually complained to the DOW about it and the outfitter got sanctioned for it, as apparently they had a pattern of similar behavior (how dare these DIY guys try and hunt in our area??!!). So, yah, if I see outfitters I won't camp within a mile or two at the least, 500 yards would be way too close to me. This is also on a ridge that often holds 5-6 longstanding locals camps, that are mindful and respectful of each other, and give each other wide berths, even though we camp within a 1/4 mile or so of each other.