I have a number of cans in different formats. For hunting, you want a direct thread can. The simple option is to have something like the Gemtech Tracker that uses a fixed 5/8-24 mount. That is fine if it works for your rifles. If you have guns with barrel profiles that are less than 5/8" at the muzzle, you will have to have someone solder or pin and weld on a collar to get it up to 5/8". I have one fixed mount can, and while I like its simplicity, I have several rifles with slimmer barrels, and I don't want to go the collar route.
My Wby Mk V Ultra Lightweight in .30-06 is at the gunsmith bering threaded 1/2-28 at the moment. It has a slim, fluted barrel and weighs less than 6 lbs. I did not want to have to attach a clunky adapter to the front. My Winchester Model 70 Super Grade in 300 Win Mag has also been threaded 1/2-28, and I also have a Wby Vanguard in 6.5CM that came from the factory threaded 9/16-24.
In addition to my Tracker, I own a SilencerCo Harvester 30 and just got a SilencerCo Scythe Ti. Both use interchangable direct-thread mounts. I have 5/8-24, 9/16-24, and 1/2-28 mounts for them, and that covers all the bolt guns I want to use them on.
The advantage of direct thread over quick detach in my mind is that it saves weight. The muzzle device and mount for a QD system are usually fairly chunky and made of steel because they are designed for rapid or full auto fire on tactical type rifles. I have some cans that use that style of attachment, but they are for my AR's. For hunting, I prefer direct thread.